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ARB in practice of cardiologists: an alternative to ACE-I or best choice?
The article deals with the use of angiotensin receptor blocker II (ARB) in practice of cardiologists. Ideas of the leading cardiologists are discussed. Main mistakes regarding the use of ARB are described in the form of myths and their revelations. Large evidence base of their efficacy and safety is submitted. There is a focus on clinical effectiveness and accessibility of a single generic drug irbesartan of domestic producers (Irbetan, PC “Kyiv Vitamin Factory”). Evidence-based medicine data on the possible benefits of ARB in certain categories of patients is demonstrated; this allows to individualize antihypertensive therapy, improve its tolerability, patient compliance and prognosis.
Key words: angiotensin receptor blocker II, antihypertensive therapy, irbesartan, Irbetan.